CREST Syndrome is a form of scleroderma that involves Calcinosis (calcium deposits in soft tissue), Raynaud's Syndrome (a syndrome characterized by discoloration of extremities), Esophageal dysmotility (difficulty swallowing), Sclerodactyly (hardening and thickening of the skin on fingers and toes), and Telangiectasia (permanent, visible dilation of small blood vessels), forming the acronym CREST. You can find more information here: http://emedicine.medscape.com/article/1064663-overview
